BioISI Post Graduate Seminars

Auditório da FCiências.ID, Lisboa

Por Tânia Marques e Diana Pimentel (BioSYS PhD Program).


An integrative approach to tissue-specific effects of miRNA regulatory networks - Tânia Marques

MicroRNAs or miRNAs are small noncoding RNAs with a major role in post-transcriptional regulation of gene expression. miRNAs become part of the RISC complex which binds to miRNA responsive elements located predominantly in the 3’UTRs of target mRNAs through base-pairing interactions involving the miRNA seed sequence leading to degradation or translational inhibition of the mRNA molecule. Even though the basic mechanisms for miRNA action have been described, we are still unable to efficiently predict the impact of these molecules on cellular function. miR function has been proposed to be regulated by endogenous competing RNAs, including both coding and noncoding RNA molecules. This suggests that the ability of a given miRNA to act upon a target is dynamically influenced by the transcriptome environment it is in, in addition to the binding affinity it displays to different targets. Thus, when predicting targets for a miRNA, the context in which it is expressed needs to be accounted for. The aim of this work is to comprehensively understand the interaction dynamics between microRNAs and their target transcriptome across different conditions. This will be achieved by dissecting miRNA regulatory networks through correlation analysis between miRNA, mRNA and predicted targets in public datasets for different tissues and conditions.

Transcriptional and metabolic regulation of grape berry metabolism upon powdery mildew infection - Diana Pimentel

Grapevine (Vitis vinifera L.) is very susceptible to several diseases and one of the most problematic is powdery mildew (PM). PM is caused by the obligate biotrophic fungus Erysiphe necator and it affects grapevine yield and berry quality. In this study, naturally infected and control grapes from Carignan variety were collected at green (EL33) and véraison (EL35) stages and metabolic and transcriptomic changes upon PM infection of susceptible grapes were analyzed. Metabolic profiling of control and infected berries was performed by gas chromatography coupled to electron impact ionization/time-of-flight mass spectrometry (GC-EI/TOF-MS) and by solid phase microextraction (SPME) associated with GC-EI-MS. Thirty-six metabolites showed differential content comparing either infected and control samples or green and véraison stages. Among these, twenty were shown to be positive markers of infection including five metabolites that were undetected in control samples. RNAseq analysis was performed to access the expression profile of PM infected and control berries at both stages and 4275 genes were identified as differentially expressed due to infection and/or ripening, and they are mainly associated with response to biotic stress, secondary metabolism (phenylpropanoid and terpene pathways) and hormone metabolism, including salicylic acid and jasmonates. Altogether, these data suggest a metabolic and transcriptomic reprogramming upon infection with PM in particular at green stage.

17h00
BioISI - Instituto de Biossistemas e Ciências Integrativas
Imagem ilustrativa dos cursos avançados cE3c 2019/2020

Deadline for Applications: November 22nd, 2019.

André Filipe Pereira Rodrigues defende a tese "Human-powered smartphone assistance for blind people".

Por Pedro Freitas (DHFC - Ciências ULisboa e CIUHCT - ULisboa).

A razão de ouro - uma perspetiva histórica

Fotografia de um docente no contexto de uma aula

Neste workshop iremos abordar esta nova abordagem que aplica os mesmos fundamentos do Flipped classroom - já confirmados pela investigação como tendo benefícios na aprendizagem - à dinâmica da sala de aula, sem trabalho autónomo extra-aula para os alunos.

Joana Madeira Hancock defende a tese "The sea turtles of São Tomé and Príncipe: Ecology, genetics and current status of distinct species nesting on an oceanic archipelago".

Imagem ilustrativa do evento, acompanhada do respetivo título

Concerto solidário, pelo Coro do Grupo Desportivo do Banco de Portugal e pelo Banco de Sons, com a possibilidade de serem efetuados donativos a favor da 

Satélites de Júpiter: Um projeto de astronomia experimental histórica I

Este seminário é um curso livre, aberto à comunidade académica e a todos os interessados, com entrada gratuita.

Imagem ilustrativa do ciclo de conferências, acompanhada do respetivo programa

No âmbito dos 500 anos da viagem de Fernão de Magalhães e da eleição de Lisboa como capital europeia verde em 2020, o Instituto de Estudos Académicos Adriano Moreira organiza um ciclo de conferências, de entrada livre, dedicado à "Sustentabilidade do Homem no planeta Terra

Luís Filipe Rodrigues Batista defende a tese "Structure and tectonics of the crust and Moho discontinuity of the Gloria Fault and Terceira Rift (S. Miguel) along the Nubia-Eurasia plate boundary".

Curso de introdução ao software R, lecionado em 4 módulos a decorrer nos dias 28 de janeiro e 4, 11 e 18 de fevereiro.

 

Programa:

Ana Sofia Ribeiro de Oliveira defende a dissertação "How high and low nesting season densities affect the patterns of nest site preferences and nest site fidelity of Caretta caretta, on Maio island, Cape Verde".

Vanessa Sofia Alegria Mendonça defende a tese "Functioning of coastal food webs - intertidal rock pools as a case-study".

Título do evento, sobre uma fotografia de uma aluna a utilizar binóculos

A Universidade de Lisboa preparou diversas atividades para te ajudar a perceber qual o teu futuro profissional. Vem descobrir a ULisboa!

Mesa redonda com a participação de Ana Margarida Nunes (CIUHCT), Cristina Luís (CIUHCT), Davide Vecchi (CFCUL, GI2), Lorenzo Baravalle (CFCUL, GI2), Mara Almeida (CFCUL, GI3), Maurizio

Imagem ilustrativa do evento, acompanhada de informações diversas (título, orador, dia, hora e local)

Apresentação por Bruno Jacinto (CFCUL) no âmbito do “Reasoning Seminar” do CFCUL.

Organização: António Zilhão (CFCUL).

Joana Maria dos Reis Franco Cruz defende a tese "Copepod communities and secondary production in Portuguese coastal waters".

Fotografia de alunos

A Universidade de Lisboa promove o Dia Aberto M23, um evento que pretende aproximar o público adulto do meio universitário.

Days in Logic will take place in Lisbon (FCUL) in January 30 and 31 and in the morning of February 1, 2020.

Logótipo Portugal 2020, sobre um fundo branco

No âmbito do Portugal 2020 encontra-se a decorrer o prazo de candidatura ao Sistema de Incentivos à Investigação e Desenvolvimento Tecnológico (SI I&DT) para projetos a desenvolver em Copromoção no âmbito da I&D Empresarial.

Por Gonçalo Oliveira (Universidade Federal Fluminense - UFF).

David García-García defende a tese "Schur Averages in Random Matrix Ensembles".

We begin with an introduction to R and provide a protocol for data exploration to avoid common statistical problems. We will discuss how to detect outliers, deal with collinearity and transformations.

Catarina Almeida de Albuquerque defende a dissertação "Detection and characterization of Dichelobacter nodosus from sheep with different clinical manifestations of Ovine Footrot".

Páginas