BioISI Post Graduate Seminars

Auditório da FCiências.ID, Lisboa

Por Tânia Marques e Diana Pimentel (BioSYS PhD Program).


An integrative approach to tissue-specific effects of miRNA regulatory networks - Tânia Marques

MicroRNAs or miRNAs are small noncoding RNAs with a major role in post-transcriptional regulation of gene expression. miRNAs become part of the RISC complex which binds to miRNA responsive elements located predominantly in the 3’UTRs of target mRNAs through base-pairing interactions involving the miRNA seed sequence leading to degradation or translational inhibition of the mRNA molecule. Even though the basic mechanisms for miRNA action have been described, we are still unable to efficiently predict the impact of these molecules on cellular function. miR function has been proposed to be regulated by endogenous competing RNAs, including both coding and noncoding RNA molecules. This suggests that the ability of a given miRNA to act upon a target is dynamically influenced by the transcriptome environment it is in, in addition to the binding affinity it displays to different targets. Thus, when predicting targets for a miRNA, the context in which it is expressed needs to be accounted for. The aim of this work is to comprehensively understand the interaction dynamics between microRNAs and their target transcriptome across different conditions. This will be achieved by dissecting miRNA regulatory networks through correlation analysis between miRNA, mRNA and predicted targets in public datasets for different tissues and conditions.

Transcriptional and metabolic regulation of grape berry metabolism upon powdery mildew infection - Diana Pimentel

Grapevine (Vitis vinifera L.) is very susceptible to several diseases and one of the most problematic is powdery mildew (PM). PM is caused by the obligate biotrophic fungus Erysiphe necator and it affects grapevine yield and berry quality. In this study, naturally infected and control grapes from Carignan variety were collected at green (EL33) and véraison (EL35) stages and metabolic and transcriptomic changes upon PM infection of susceptible grapes were analyzed. Metabolic profiling of control and infected berries was performed by gas chromatography coupled to electron impact ionization/time-of-flight mass spectrometry (GC-EI/TOF-MS) and by solid phase microextraction (SPME) associated with GC-EI-MS. Thirty-six metabolites showed differential content comparing either infected and control samples or green and véraison stages. Among these, twenty were shown to be positive markers of infection including five metabolites that were undetected in control samples. RNAseq analysis was performed to access the expression profile of PM infected and control berries at both stages and 4275 genes were identified as differentially expressed due to infection and/or ripening, and they are mainly associated with response to biotic stress, secondary metabolism (phenylpropanoid and terpene pathways) and hormone metabolism, including salicylic acid and jasmonates. Altogether, these data suggest a metabolic and transcriptomic reprogramming upon infection with PM in particular at green stage.

17h00
BioISI - Instituto de Biossistemas e Ciências Integrativas
Logótipo ERC - European Research Council

Ciclo de sessões de divulgação das oportunidades ERC - European Research Council para 2020.

 

ERC Days @ Porto, 25 e 26 de junho

Ações de Formação Pedagógica para Docentes

O objetivo deste curso é apoiar o desenvolvimento docente, incentivando a reflexão sobre estratégias de ensino que podem ser utilizadas no ES.

Por Byungnam Kahng (Department of Physics and Astronomy, Seoul National University).

Por Fabio Deelan Cunden (University College Dublin).

João de Sousa Alves defende a dissertação "CAN FD: a communication network for future avionic systems".

Almoços com Ciências

Especialistas de Ciências ULisboa conversam informalmente sobre temas atuais, durante o almoço.

Por Cristiana Palmela Pereira (Faculdade de Medicina Dentária da Universidade de Lisboa).

The main goal of this 2-days workshop is to gather  researchers, post-docs and students from all Europe, working on Planetary Science studies to discuss about several topics related with Planetary Atmospheres (including exoplanets), and promote collaborations on the basis

Ciclo de colóquios no âmbito da Exposição "E3 - Einstein, Eddington e o Eclipse"

Colóquio por Marta Macedo (Instituto de Ciências Sociais, Universidade de Lisboa).

O evento conta com a participação, na qualidade de keynote speaker, de Filipe Duarte Santos (Ciências ULisboa).

Conferências CIUHCT "Ricardo Carlos Smith, a forgotten pioneer of Portuguese horticulture"

As Conferências do CIUHCT são um ciclo de palestras organizado anualmente pelo CIUHCT acerca de assuntos de História das Ciências e da Tecnologia.

Logotipo Lisboa 2020

O Programa Lisboa 2020 abre concursos para Investimentos em Infraestruturas Tecnológicas.

Frontiers in E3: 5th cE3c Annual Meeting

The cE3c 5th Annual Meeting will take place on July 1-2 2019, at the National Museum of Natural History and Science.

Verão na ULisboa 2019

A edição de 2019 da iniciativa Verão na ULisboa decorre nas semanas de 01 a 05 de julho (alunos do 10.º,11.º e 12.º ano) e de 08 a 12 de julho (alunos do 7.º, 8.º e 9.º ano).

As provas, requeridas por José Manuel Lourenço Coutinho Afonso, decorrem nos dias 01 e 02 de julho de 2019.

Cursos Avançados cE3c 2018/2019

Under the general framework of Global Change Ecology, the goal of this course is to provide the participants with the most recent and practical knowledge on the use of Functional Diversity.

Ciclo de colóquios no âmbito da Exposição "E3 - Einstein, Eddington e o Eclipse"

Colóquio por Duarte Pape (Paralelo Zero).

Doutoramento em História e Filosofia das Ciências

Doutorando: Luís Miguel Campos Ribeiro.

Tema da tese e alvo de discussão oral: O candidato apresentará o Seminário Doutoral III.

Ciência 2019 - Encontro com a Ciência e Tecnologia em Portugal

O evento procura reunir a comunidade científica em torno de um programa multidisciplinar que aborda os desafios científicos e societais atuais, tendo por base os 17 Objetivos de

Cursos Avançados cE3c 2018/2019

Currently, climate changes or alterations are known to be reflected on the stable isotope ratios of Hydrogen, Nitrogen, Carbon, Oxygen and Sulphur present in atmospheric gas forms, fresh or ocean water, as well as in plants and animals and organic matter in the soil.

Izabella Campolina Silva e Hemprich apresenta o trabalho de projeto "Consortia optimization for European Space Agengy proposals based on cognitive computing".

Escola de Verão de Energia

Imagina que era possível experimentar um curso universitário antes de concorreres ao ensino superior.

Páginas